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当前位置: 首页 » 食品资讯 » 外讯导读 » 欧盟评估芬氏纤维微菌菌株AE-AMT生产的α-淀粉酶的安全性

欧盟评估芬氏纤维微菌菌株AE-AMT生产的α-淀粉酶的安全性

放大字体  缩小字体 时间:2022-08-04 10:29 来源:食品伙伴网 作者: 泽夕   
核心提示:2022年8月3日,欧盟食品安全局就一种α-淀粉酶(α‐amylase)的安全性评价发布意见。
   食品伙伴网讯  2022年8月3日,欧盟食品安全局就一种α-淀粉酶(α‐amylase)的安全性评价发布意见。
 
  据了解,这种食品酶是由芬氏纤维微菌菌株AE-AMT生产的,旨在用于麦芽三糖生产的淀粉加工中。
 
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏和诱发反应的风险,但这种情况发生的可能性很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-amylase (4-α-d-glucan glucanohydrolase; EC 3.2.1.1) is produced with the non-genetically modified Cellulosimicrobium funkei strain AE-AMT by Amano Enzyme Inc. The food enzyme is free from viable cells of the production organism. It is intended to be used in starch processing for maltotriose production. Since residual amounts of total organic solids (TOS) are removed by purification steps applied during starch processing, the estimation of a dietary exposure is considered unnecessary. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level at the highest dose of 230 mg TOS/kg body weight (bw) per day. Similarity of the amino acid sequence of the food enzyme to those of known allergens was searched and nine matches were found. The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood is considered low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
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日期:2022-08-04
 
 
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