甜菊糖苷生产工艺包括两个主要过程：第一步采用水相提取甜叶菊叶，之后采用离子交换色谱法纯化，产生甜菊糖苷初提物；第二部采用甲醇或乙醇进行重结晶制得含量不少于95%的甜菊糖苷成品。

 

    甜菊糖苷为白色至淡黄色粉末，甜度大约为蔗糖的200至350倍（以5％的蔗糖相当值），易溶于微溶于水。品质指标主要包括：总灰分≤1%，干燥失重≤6%（105°C，2h），不溶性固形物≤200mg/kg甲醇或5000mg/kg乙醇，砷≤1mg/kg，铅≤1mg/kg。新条例自发布20日后生效。

 

    部分原文报道如下：

 

    The manufacturing process comprises two main phases: the first involving water extraction of the leaves of the Stevia rebaudiana Bertoni plant and preliminary purification of the extract by employing ion exchange chromatography to yield a steviol glycoside primary extract, and the second involving recrystallisation of the steviol glycosides from methanol or aqueous ethanol resulting in a final product containing not less than 95 % of the below identified 11 related steviol glycosides, in any combination and ratio.

 

    The additive may contain residues of ion-exchange resins used in the manufacturing process. Several other related steviol glycosides that may be generated as a result of the production process, but do not occur naturally in the Stevia rebaudiana plant have been identified in small amounts （0,10 to 0,37 % w/w）。

 

    原文链接：http://eur-lex.europa.eu/legal-content/EN/TXT/?uri=uriserv:OJ.L_.2016.278.01.0037.01.ENG&toc=OJ:L:2016:278:TOC