根据欧盟委员会第396/2005号法规第12章，欧盟食品安全局审查了杀菌剂propineb的最大残留限量。由于缺乏化合物PDA的完整毒理学特征、植物中代谢物propineb-DIDT和加工商品中PDA的暴露数据，并且考虑到与CXLs相关的proineb-MRL是基于欧盟的用途，这些用途在不更新后被撤销，不再适用，EFSA无法对这些最大残留限量进行评估，因此不建议将其纳入欧洲法规。

 

　　部分原文报道如下：

 

　　According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance propineb. Although this active substance is no longer authorised within the EU, due to insufficient information in order to conclude on the consumer risk assessment for the active substance, the toxicity of the metabolite propane‐1,2‐diamine (PDA) the impact on non‐target organisms and the risk to honeybees, MRLs based on the use of propineb were established by the Codex Alimentarius Commission (codex maximum residue limits; CXLs) and are still in place. Additionally, propineb has potential endocrine‐disrupting properties related to the hazards of its major metabolite 4‐methylimidazolidine‐2‐thione (PTU). Lacking a full toxicological characterisation for the compound PDA, exposure data for metabolites propineb‐DIDT in plants and PDA in processed commodities and considering that propineb‐MRLs correlated to CXLs were based on EU uses that were withdrawn following the non‐renewal and are no longer in place, it was not possible for EFSA to perform an assessment of these MRLs and their incorporation in European legislation cannot be recommended. Nevertheless, available data allowed EFSA to propose a marker residue and a limit of quantification (LOQ) for enforcement against potential illegal uses.

 

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