食品伙伴网讯  2019年11月7日，欧盟食品安全局发布关于来自两种转基因谷氨酸棒杆菌（Corynebacterium glutamicum）菌株的L-赖氨酸盐酸盐（L-Lysine Monohydrochloride）和L-赖氨酸浓缩液体（concentrated liquid l‐lysine）安全性和有效性的评估结果。

 

　　据了解，两种产生L-赖氨酸盐酸盐（盐酸，最低98.5%）和L-赖氨酸浓缩液体（碱，最低50%）的基因谷氨酸棒杆菌菌株为NRRL‐B‐67439 或 NRRL B‐67535，该添加剂旨在用于所有动物物种的饲料或饮用水中。

 

　　部分原文报道如下：

 

　　The European Commission asked EFSA for an opinion on the safety for the target animals, consumer, user and the environment and on the efficacy of a l‐lysine monohydrochloride （HCl, minimum 98.5%） and of a concentrated liquid l‐lysine （base, minimum 50%） produced by genetically modified strains of Corynebacterium glutamicum （NRRL‐B‐67439 or NRRL B‐67535）。 They are intended to be used in feed or water for drinking for all animal species and categories. Neither viable cells of the production strains C. glutamicum strains NRRLB‐67439 or NRRL B‐67535; nor their recombinant DNA were detected in the final products. Therefore, those products do not pose any safety concern associated with the genetic modification of the production strains. l‐Lysine HCl and concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRLB‐67439 or NRRL B‐67535 are considered safe for the target species, for the consumer and for the environment. l‐Lysine HCl produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535 is considered not irritant to skin or eyes and not a skin sensitiser. In the absence of data, the FEEDAP Panel cannot conclude on the potential toxicity by inhalation of l‐lysine HCl produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535. Concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535, due to its high pH （10.7 and 10.9, respectively） is anticipated to be corrosive to skin and eyes and poses a risk by inhalation. l‐Lysine HCl and concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRLB‐67439 or NRRL B‐67535 are considered as efficacious sources of the essential amino acid l‐lysine for non‐ruminant animal species. For the supplemental l‐lysine to be as efficacious in ruminants as in non‐ruminant species, it would require protection against degradation in the rumen.

 

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