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欧盟评估乳糖-N-新四糖作为新型食品的安全性

放大字体  缩小字体 时间:2020-11-20 11:36 来源:食品伙伴网 作者: 泽夕   
核心提示:2020年11月19日,据欧盟食品安全局(EFSA)消息,欧盟营养、新型食品和食物过敏源(NDA)研究小组就乳糖-N-新四糖(lacto‐N‐neotetraose)作为新型食品的安全性发表科学意见。
   食品伙伴网讯  2020年11月19日,据欧盟食品安全局EFSA)消息,欧盟营养、新型食品和食物过敏源(NDA)研究小组就乳糖-N-新四糖(lacto‐N‐neotetraose)作为新型食品的安全性发表科学意见。
 
  据了解,乳糖-N-新四糖是由大肠杆菌BL21的衍生菌株生产的。经过评估,专家小组得出结论,在提议的使用条件下,乳糖-N-新四糖作为新型食品是安全性的。部分原文报道如下:
 
  Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the change in the production process and specifications of lacto‐N‐neotetraose (LNnT) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) LNnT but also contains lactose, lacto‐N‐triose II (LNT II), para‐lacto‐N‐neo‐hexaose (para‐LNnH) and other related carbohydrates. The NF is produced by fermentation with two genetically modified strains of Escherichia coliBL21. LNnT when chemically synthesised or produced by microbial fermentation using another E. coli strain (K‐12) is already authorised and included in the EU list of NFs. This application is limited to a change in the manufacturing process and specifications while target population, uses and use levels and consequently the anticipated intake do not change. The information provided on the manufacturing process, including the absence of DNA from the producing microorganisms, composition, identity and specifications of the NF do not raise safety concerns. Particularly, the proposed changes in the specifications are limited to a slightly higher ash content and limits for the presence of yeast and moulds, while specifications for methanol and LNnT fructose isomer have been removed. Food supplements are not intended to be used if other foods with the added NF or breast milk for young children are consumed on the same day. The Panel concludes that lacto‐N‐neotetraose (LNnT) as a NF when produced by fermentation with two genetically modified strains of E. coliBL21 is safe under the proposed conditions of use.
 
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日期:2020-11-20
 
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